It can work. Alicia's got the talent and the looks.

According to
Page Six, Oprah Winfrey confirmed that Alicia Keys will be starring in an upcoming Lena Horne biopic that originally had Janet Jackson attached to it. Oprah will be producing under her Harpo Films banner most likely in co-production with Alicia's existing film production company Big Pita, Little Pita. “We’re going to start filming next year,” Oprah said of her Lena Horne biopic. “And we’ve got Alicia.”
Oprah's Harpo Films is releasing the upcoming Denzel Washington pic
The Great Debaters while Alicia's Big Pita, Little Pita Productions which was formed in a production deal with Disney, still is waiting to get two potential films developed, the modern day fairy tale
Bell, Book and Candle and the Deep-South film
Catfish.